I went the other way a few years ago. As Gord says, need a 3-crew minimum for up-bound. More would make it even easier. It’s fairly straightforward, but tiring.
Have good gloves for the lines; some are pretty rough and ugly. Upbound turbulence is said to be significant in some of the locks, so a
fender board is probably a good idea.
I think it took us about nine hours to do the whole system (14 from time we checked in). We ended up going through the night, which in some ways is easier.