I went through the system from Ithaca NY to Lake Champlain in 2013,
single handed on a
C&C 29. Not an issue. However, depending on the time of year, you may be dealing with some strong currents in places. I went through in May and the spring run off was close to peak. I actually had to transit rapids getting into one lock Northbound on the
Hudson. Luckily, I was heading into the
current. Would have been a different story the other direction.
As Stated, gloves are a must. I did use a
fender board and glad I did as it protected my fenders from the lock walls. Very pleasant and interesting transit.