Depends if you're asking about clientele (whether new customers or existing customers) and how to support them... or, are you asking whether it's feasible from a technology aspect (Internet connectivity,
WiFi, cellular data, laptops, a server running applications, power for all devices, etc.)
If you're asking about clientele... then I don't think it matters unless you had clients coming to YOU in the past. If you
work remotely or you go to THEM, then it's fine. A post office will always be within a short drive, a UPS/FedEx location may also be an option, and for everything else you can have a car parked somewhere, a rental car, or Uber/Lyft/taxi.
If you're asking about the technology... it depends on where you'll be
living aboard. In a marina with a strong marina
WiFi? On anchor/mooring isolated from everyone else? Either way, video conferencing has jumped leaps and bounds in the past nine months or so. A reliable and strong
Internet connection is pretty much everywhere except if you go
offshore. For power, you'd need something for your
electronics... do you really need a
desktop? A
laptop with an extra
monitor can give you a dual-screen setup that a lot of people in normal offices don't have. As for an application server (Windows Server 2019, QuickBooks server, etc.), you can always rent it out from Amazon AWS.
I think it's feasible and something that I'll be striving for in the future... for now, I already
work about 20-25% from my
boat. I teach Math and Physics remotely via Zoom and FaceTime. It works great! Albeit, I am in a marina and always have
shore power and a strong
Internet connection.
Good luck and go for it! I'm positive you'll love it and get some new experiences under your belt.