I would vote for Prince William Sound. Look up Seward, and Whittier (you can drive from Anchorage to both places) As well as Valdez and Cordova as possible towns with charter boats available.
SE Ak. is a rain forest, and the sailing is up channel and down channel. At least that is how the wind
PWS has all or more of the amazing, whales, birdlife, glaciers, and all. Many, many good anchorages
....all around better than SE in my opinion