Marc makes a good point about the northers that are not uncommon, usually about three days duration, during this time and on into the winter
, but there should be no difficulty in choosing to wait out these events
just as avoiding a late tropical storm. If you're taking coastal hops, the longest leg would be an overnight across Florida's "Big Bend" from areas near Appalachicola to Anclote Key or a shorter choice from St. Marks to Cedar Key. Your selections in this area depend on your draft
. Once to Tarpon Springs (Anclote Key) you are back to easy half day choices offshore
or the ICW
. 'many beautiful stops if you're not rushed.