Covid vaccination status for CF members

[Montanan]

Oxford/AstraZeneca vaccine may help prevent transmission and that a further delayed second booster inoculation may be beneficial.

A COVID-19 vaccine developed by England's University of Oxford and British-Swedish pharmaceutical giant AstraZeneca not only protects people from serious disease and death but also may have a substantial effect on transmission of the virus, according to a new study that has not been peer-reviewed. A preprint published Tuesday, which is currently under peer review at the medical journal The Lancet, University of Oxford researchers said an analysis of further data from ongoing clinical trials of the two-dose vaccine shows a 67% reduction in positive swabs among those who received a single dose. It's the first study to document evidence that any COVID-19 vaccine can reduce transmission of the virus.
Researchers said the analysis also reveals the vaccine efficacy is higher at longer prime-boost intervals and that a single dose of the vaccine is 76% effective from 22- to up to 90-days post vaccination.

https://abcnews.go.com/Health/live-u...posts_card_hed

[tarian]

Tell that to Mr Macron from France who called it a quasi vacine from the UK , yet one of the worlds top universities have stood by their vacine and the data which is coming in now as the UK passses 10 million vaccinations. I would assume that most facines do the ame Z the data rolls in

[capn_billl]

The AstraZeneca while it has a new unique manufacturing process (GM'ing the common cold to add Covid markers), is a more conventional type of vaccine that operates closer to existing vaccines with a tried, and proven safety, and effectiveness.

https://www.astrazeneca.com/media-ce...ii-trials.html

AND it doesn't need the extraordinary cooling the mRNA vaccines need.

AND the fact that this virus is genetically modified, while concerning, it isn't much different than all most modern vaccines which contain the virus in a modified state to prevent getting the disease.

Much safer than injecting you with a "LIVE" virus.

[Montanan]

One vaccine dose might be enough for COVID-19 survivors

COVID-19 survivors might only need one shot of the new vaccines from Moderna Inc and Pfizer/BioNTech, instead of the usual two doses, because their immune systems have gotten a head start on learning to recognize the virus, according to two separate reports posted this week on medRxiv ahead of peer review. In one study of 59 healthcare workers who recovered from COVID-19 and received one of the vaccines, antibody levels after the first shot were higher than levels usually seen after two doses in people without a history of COVID-19. In a separate study, researchers found that 41 COVID-19 survivors developed "high antibody titers within days of vaccination," and those levels were 10 to 20 times higher than in uninfected, unvaccinated volunteers after just one vaccine dose. "The antibody response to the first vaccine dose in individuals with pre-existing immunity is equal to or even exceeds" levels found in uninfected individuals after the second vaccine dose, the authors of that paper said. "Changing the policy to give these individuals only one dose of vaccine would not negatively impact on their antibody titers, spare them from unnecessary pain and free up many urgently needed vaccine doses," they said.

https://bit.ly/3je4Zv4; https://bit.ly/2YG0EYf

[Hoodsail]

Originally Posted by tarian

There is no vacine to said common cold because their is no such thing as one common cold, all viruses mutate some good for humans some not good, but memory T cells and B cells are what is in the name memory , this memory allows the body to react to a viral mutil
Mutation like the common cold because it regoinses the majority of the RNA and fights it quicker and more effeictly.
Covid 19 comes from the same strain as a common cold per sei the virus known as corona viruses because of the corona that sorounds them.
Corona viruses are prevalent in bats and this is thought were some come from and mutate and jump from animal to human potentially via a vector of a other animal
If the human body has experienced corona viruses in the past their is a antibody response first if this p
Doesn't work then T and B cells are activated with memory to identify the virus which has invaded cells and attacks them.
As we get older , our immune response weakens drastically as T and B cells are made in the bone marrow, also if we have severe immune diseases like type 2 diabetes this puts pressure on the immune system to fight.
many of the deaths are older and unwell people with low immunity, were as children with strong immune systems are least affected,
People who are obese are at risk because although they might not be diabetic they are on the verge of it by putting extreme pressure on their bodies.
Yes healthy fit people die, but there is no evidence to say that they may have a weak immune system and never knew about it.and statistically the numbers are low.
This virus creates two systems of death, like flu or any respiratory virus can it causes fliud in the lungs and an over excited immune response that attacks your own body , an immune cascade

It is worth noting and can be clarified via the CDC statistics that a greater age range die of seasonal flu than covid . I.e children die of influenza each year.
Covid hits the oldest and the weakest in our society and kills
Any vacine that offers over 50 % more antibodies is a good vacine most influenza vacines each year which also have to be altered because of mutation normally gives around 50 to 60 % efficacy.
The key is the more that get vaccinated and lower the viral load the less heavily loaded infected people there are also once the vacine has created an immune response the body is primed to attack the virus right away , allowing the body a fighting chance .
All vacines that have been approved aroundt he world are safe and should be taken for the sake of your partner, your family member or your friends , you not only protect yourself but potentially them as well
I am a medically retired biologist I am not a virologist but this really is 2 year biology academics . It is a virus and we know how and why and what a virus does.

As for face coverings , if it offers 5 % protection extra I will take it , if a doctor gave me 50% or 55% to live what are you taking .
Keep of face book , certain medical journals and twitter it will drive you mad.
Yes the lancet is one of the worlds top medical journals but it also likes to create a little storm with its publications some of which in the past have found to be wrong, for example M.e and graded excerise and the MMR jab that causes autism.
Beware what you read in scientific papers and find the counter argument.

Agree with most of what you've noted above, but to dismiss scientific papers and "...find the counter argument." goes to far....Where would you suggest you search for that counter? No question, that journals make mistakes such as the autism piece that was published (you note) and eventually retracted, but damage done...the Letters conversation in journals that follows a published trial/scientific observation are valuable in that they can highlite potential flaws/assumptions/current knowledge. And always do not use one sole source of info, journals included. Hoping to get vaccinated here in Connecticut, USA in a month! yea... ps..russian vx data just published in lancet!!

[GordMay]

Nobody is using (nor proposing) live (unmodified) virus inoculation, against covid-19.


Several different types of potential vaccines for COVID-19 are in development, including:

- Inactivated or weakened virus [LAVs] vaccines, which use a form of the virus that has been inactivated or weakened so it doesn’t cause disease, but still generates an immune response.
Live-attenuated vaccines use a living, but weakened version of the virus, or one that’s very similar. The measles, mumps and rubella (MMR) vaccine, and the chickenpox and shingles vaccine are examples of this type of vaccine. India’s “COVI-VAC” [1] is a single-dose, intranasal, live-attenuated vaccine against COVID-19. Meissa’s “MV-012-968" is another.

- Protein-based vaccines, which use harmless fragments of proteins or protein shells that mimic the COVID-19 virus to safely generate an immune response.
- Viral vector vaccines, which use a virus that has been genetically engineered so that it can’t cause disease, but produces coronavirus proteins to safely generate an immune response.

- RNA and DNA vaccines, a cutting-edge approach that uses genetically engineered RNA or DNA to generate a protein that itself safely prompts an immune response.

None of the currently authorized and recommended COVID-19 vaccines, or COVID-19 vaccines currently in development, contain the live virus that causes COVID-19. This means that a COVID-19 vaccine cannot make you sick with COVID-19.

If your body develops an immune response, there is a possibility you may test positive on some antibody tests[2], but not on viral tests[3].

[1] Codagenix Inc “NOVI-VAC” for SARS-CoV-2 ➥ https://codagenix.com/vaccine-programs/covid-19/
Meissa “MV-012-968" ➥ https://www.biospace.com/employer/54...vaccines-inc-/

[2] Antibody or serology tests look for antibodies in your blood, to determine if you had a past infection with the virus that causes COVID-19.

[3] Viral tests: A viral test checks specimens from your nose or your mouth (saliva) to find out if you are currently infected with SARS-CoV-2, the virus that causes COVID-19.
- Nucleic acid amplification tests (NAATs) detect the virus’s genetic material, and are commonly used in laboratories. NAATs are generally more accurate, but sometimes take longer to process, than other test types.
- Antigen tests detect viral proteins, and are generally not as sensitive as NAATs, particularly if the antigen test is used on someone without COVID-19 symptoms. If you have a positive or negative antigen test, your healthcare provider may need to confirm the test result with a NAAT.

[valhalla360]

Originally Posted by capn_billl

My understanding of viral infections is your body builds antibodies that (remember) the virus.

That doesn't mean you can't "catch" the virus, just that the second exposure will result in milder symptoms, and a shorter recovery, and a smaller chance of dying from it.

Mea Culpa...I used poor terminology in the post you referenced.

Yes, you can still be infected even if you have "immunity" but your body fights it off much faster and more effectively with little collatteral damage (assuming the "immunity" is strong).

[capn_billl]

IF getting Covid-19 gives you an immune response why do you need the vaccine at all?

[Catalier]

Originally Posted by capn_billl

IF getting Covid-19 gives you an immune response why do you need the vaccine at all?

Because it's better to have not had Covid at all. It kills some of the people who get it, you know

[Woodland Hills]

Originally Posted by capn_billl

IF getting Covid-19 gives you an immune response why do you need the vaccine at all?

Which has a greater chance of death: the vax or Covid? Are you feeling lucky?

[sv_pelagia]

Originally Posted by capn_billl

IF getting Covid-19 gives you an immune response why do you need the vaccine at all?

Because natural infections (which most may be light infections, thus asymptomatic) likely only provides short(er) lived immunity.

And, as said, far better to never get COVID-19 at all.

[Calif.Ted]

I'm going to Disneyland !!!! signed up January 15th and have appointment for vaccine today. Haven't been to Disneyland in decades maybe I'll get a hat too.

[Midwesterner]

Originally Posted by Woodland Hills

Which has a greater chance of death: the vax or Covid? Are you feeling lucky?

Modern vaccines are always safer than the disease they prevent. I've had both shots of the Pfizer vaccine and have had no problems. I work in a hospital that vaccinated several hundred people with not serious issues. In this same county we've had 107 deaths from Covid. Tomorrow, we will hit 7,500 deaths in our entire state.

I'll take vaccines any day. I've had my tetanus, shingles, hepatitis, influenza and Covid-19 vaccines. And the shingles won't kill me, but I've watched people suffer from it. I'm even going in to get the newer improved shingles vaccine.

[Montanan]

Some positive news.

US hospitalizations for Covid-19 are at lowest point since Thanksgiving

Across the U.S., 91,000 patients are in the hospital with COVID-19-- the lowest number since Nov. 28, which was two days after Thanksgiving, according to ABC News’ analysis of data compiled by the COVID Tracking Project.

Hospitalizations have declined by nearly 30% in the last three weeks.

In the span of three weeks, the national seven-day average of daily COVID-19 cases has declined by 45.6% -- the steepest and most consistent non-holiday-related drop in cases the U.S. has seen since the summer.

[boatman61]

So.. it looks like the EU will be taking the Vaccine Passport route.. along with the UK.