If you mean non-stop during daylight hours that's a tough ask. Your overall plan must include timing Plum Gut at slack turning to flood. That means for the six hours before reaching the Gut you'll also have favourable currents. Check your favourite tide/
current charts. I still use Eldridge.
Of course all goes out the window if
wind and
weather isn't on your side the whole trip.
Once you pass Mattituck inlet you're committed to rounding the Gut so check your numbers then.