Yes. My 740s is hooked up that way. Works great. Only problem is if you have an AIS receiver and transceiver, some devices might get confused and think you're about to collide with yourself. The Garmin doesn't seem to have that issue, but I have another device which does.
Lol im literally doing, and did, this exact chore today in the thread below. You use the blue/ grey wires from the Garmin NMEA 0183 cord to send GPS coordinates to VHF. Then you hook up your 2k network normally.