We did the reverse as we sailed from Miami
and down and around to Panama
and back to Panama
then did a 5 day sail to Jamaica
sailing 42 degs to the wind
for 5 days or so.
If you reverse it it would have been a great down hill run and very fast and miss the worse winds off the Colombia
that can make route
very uncomfortable. Oh and do not forget the major river flowing in the Carib down near the Colombia
point that will be full of logs
ect if it has rained up stream. There have been some posting
on that here someplace.