I just came across the old Prolific GPS puck that needs the Prolific USB<=>Serial driver.
On a lark, I plugged it into a newer MacBookPro M1 (arm not intel). It registered just fine, and I was able to connect it to OpenCPN via: /dev/cu.usbserial-10 at 4800 baud and I am receiving NMEA0183 data.
To find the device, I just did an 'ls /dev' on the command line looking for 'serial'.
So, on an earlier post I made where I thought support for this was completely blocked on newer MacBooks, I guess I was wrong.
I used a little thumb-sized USB-C<=>USB-A adapter to plug it into the laptop