Carpe Diem,
I've not done that
route, but would recommend "Cruising
Ports the Central American Route" by Capt. Pat Rains as the best cruising guide for
Central America. She provides good guidance on preparations, clearances etc. Our
boat is in Isla Mujeres, having cruised up Central America from
Panama over the last three seasons, and will make our crossing to MS in May. Mid-April is the beginning of the better
weather window for a GOM crossing.