Wheels,
The cable runs were high up on my list. I definitely wanted to avoid heavy, expensive DC runs all the way across the boat to the entertainment center. No matter what choice, the best way is certainly to locate the inverter close to the batts and then run the AC over, resulting in lower amps. This is definitely how it will be done.
Still thinking hard about this, since Kau Nui has so many good reasons for a large inverter (and the neatness it entails). At the same time, I might be leaning toward the smaller, cheap ones for economics and redundancy.
Still on the fence.