pretty much what vasco says - palm coast to daytona (or new smyrna beach), then to titusville or cocoa, then to vero beach.
stay a few days at vero; there's a good reason why it's come to be known as 'velcro' beach - sailors arrive boat don't leave.
then south again. you could go out at fort pierce (check the tides - there's a very strong current
in this channel) but i prefer to stay inside until lake worth
. then you may want to go outside to either fort lauderdale
, or better, miami. the reason is the number of bridges you will have to clear - it becomes very tiring.
then south through biscayne bay, out at angelfish, and on to marathon.
there are any number of good anchorages
along the way except on the section between palm beach and miami. a set of PAPER charts
(i'm biased) will reveal them....