The inside passage is one of the more beautiful places around Vancouver Island. One of the must see places on my list would be Telegraph cove, nice old whaling town. There are three narrows which have to be passed at slack tide, and I have found that the tide book, "Ports & Passes" (found at any local marina here), to be invaluable. It is good from Bellingham Wa. to Juneau Ak, giving the tides (Slack and floods for the passes) in local time (no screwing around converting to daylight saving or adding time from a base station).
As far as places to go or anchorages
to be had, all is good and too many to list, you'll have a great time, and keep an eye open for Orca whales, they transit the strait that time of year.