In my experience owning and extensively cruising a PDQ
36 and Atlantic 42 I'm a believer in galley
down. In heavy weather offshore
things have a tendency to move around. Try some short period beam seas with that galley
up and odds are some items will end up down below on their own.
If the meal I'm preparing or the dishes I'm washing
decide to leap onto the floor and slide around I'd greatly prefer to have them do so in a galley down situation when the mess can be contained. In our Atlantic 42 the stove is gimbaled fore and aft and all of our counter tops have fiddles, but it's still possible to have spills.
What else would you put down in the hulls anyway? More heads and staterooms that you won’t use that will end up filled with junk you don’t need that just kills performance.