After doing a lot of screwing around running Long USB cables
for my WIFI
I ended up using both with the powered hub at the antenna
end of the cable. I had no trouble with using a thumb drive at the end of the powered cable but the WIFI
just would not work well without a powered hub on the far end to boost the signal. Also be careful to try to run the USB separate from other wires. I ran mine at first with some AC wires and it would work for about 2 hours and then quit, and then the computer would reject the cable completely, about drove me nuts figuring that one out.
The cable would have to sit overnight by itself before I could use it again. I had to install an outlet in a aft locker to power the hub but since doing that I get a great connection, I am on it now. I am running about 24 feet.