We have an Outbound 44 (the earlier version of the 46 minus the larger stern step) and we have the Pullman forward cabin and the port nav station. So far (we have only had it one year) we love the arrangement.
The pullman berth seems to create *much* more storage
space in the forward cabin and it allows for a full-size head and separate shower forward. It does force one to sleep close to your spouse or significant other but that can be viewed as a bonus... In either case, the aft cabin is more suited to sleeping underway than either of the forward cabin arrangements.
The port nav station allows for a full-size head with separate shower stall in the aft head (starboard side). We have not had any trouble with food
leaping off the stove onto the nav station... but I understand that could be a concern. If this is truly a concern there is a sizeable partition between the two and perhaps this could be mitigated futher with a lexan
For us at least one head with separate shower was a requirement. Having two allows for a convenient place near the companion-way to hang wet weather gear
. The only configuration that makes no sense to me is the center-line queen forward with the starboard nav station -- this precludes even one shower-stall -- a huge issue for us on a live-aboard boat.
Of course this all depends on your preferences and how you will use the boat.