According to Pub. 136 you depart on N course later gradually working thru NE and E course. How far to go N and how early/much to turn E depends on the time of the year. This is basically similar to Hawaii
- Frisco route, above the high later joining the Frisco - Panama route.
All details and approx turning points in Pub 136. routes 10.83 thru 10.85. My passages are the fourth edition.
Remember the hurricane
season and look up the expected hurricane
tracks - and sail accordingly. If sailing now you will be more exposed to tropical systems risk, if sailing later then wx up N will be your bigger worry.
Make sure your wx awarness onboard is top notch, esp. if sailing during the hurricane season or in the winter.
If you are not comfortable with your wx skills, get a wx aware shore based person to support you during the passage
If you do not have Ocean Passages, drop me a PM and I can post the relevant passage