Panama to San Andreas is certainly do able (especially with plenty of range under power), though Cartagena
gives you a better wind
angle, but after that getting to Jamaica/DR takes you much harder to windward. It is a common route
to loop further West thru the NW Carib and then easterly over Cuba
. You might take a look at that as an option.
colemj, another member
here, recently sailed Panama to Jamaica
, but the windward performance of his Manta
is likely better than the Solaris.