Just my 2 cents, but going the Mujeres route
seems to add an AWFUL lot of distance to the overall route. From Slidell, you will add what, maybe 300 miles of West that you'll have to make back up on a looong southerly tack and back north, which will also add quite a bit of distance/time.
At least if you head south to the keys and then east, you have the stream on your stern for a little while anyway, rather than fighting the yucatan current
. And you also have a number of places to stop if/when weather
takes hold (winter isn't really the time to be stuck out in the middle of the western carib. There's only a smattering of options when the weather
acts up - caymans, Providencia, San Andres...not much else down that way for quite a while on a S tack out of Mujeres)
But then again, if you don't mind, or prefer stronger winds and longer legs, maybe that's the way to go. Just some thoughts....that's all...
Good luck, and enjoy.