There are as many options and combinations as the factorial of the total number of inlets IE how many different ways you can combine all the inlets like A to B, A to C, A to D, B to C, B to D, etc, etc, etc.
It would help to understand your preferences in this: saving time, bypassing boring/shallow/troublesome sections of the ICW, offshore
practice or ???
One thing to bear in mind, in many of the inlets it is a long way from the ICW out the channel to deep water
in the ocean. Often 2 - 3 hours, sometimes more. If you're trying to save time then the in and out will eat up most of the savings unless you plan a long offshore
hop like an overnight sail.
Will also depend on how far north you're starting and how far south you want to go. When I brought my boat down from New England
my outside hops were:
to Delaware Bay
- Delaware Bay to Norfolk
- Little River SC (very short hop to deep water) to Charleston
- Charleston to Brunswick
- Brunswick to St Johns River (final destination)
Most of these were to save time, some to bypass shallow sections (Charleston to Brunswick).