Sean...the east coast
guide is quite a good reference for anchorages...bridges...and shoal spots. It gives NO sailing directions or marina info (there is a separate marina info guide they put out.) Visit the website for updates to the printed guide before you leave. Also suggest a visit to the saltysoutheast cruisers website hosted by Claiborne Young for ICW updates and the boatus EAST COAST
Alerts forum by Tom Neale who posts bi weekly alerts. It's the stuff that happens after the page is printed that'll get ya on the icw. I just pencil it all in at the appropriate mile marker in my skipper
You will need something else north of the Chesapeake as a guide(s) but I assume you know that. Jack Doziers Cruising Guide to the ICW Northern Edition is pretty comprehensive.